Deficient Sleep in Mouse Models of Fragile X Syndrome

In patients with fragile X syndrome (FXS), sleep problems are commonly observed but are not well characterized. In animal models of FXS (dfmr1 and Fmr1 knockout (KO)/Fxr2 heterozygote) circadian rhythmicity is affected, but sleep per se has not been examined. We used a home-cage monitoring system to...

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Publicat a:Front Mol Neurosci
Autors principals: Saré, R. Michelle, Harkless, Lee, Levine, Merlin, Torossian, Anita, Sheeler, Carrie A., Smith, Carolyn B.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585179/
https://ncbi.nlm.nih.gov/pubmed/28919851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00280
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