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Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals

AIMS/HYPOTHESES: Reduced mitochondrial capacity in skeletal muscle has been observed in obesity and type 2 diabetes. In humans, the aetiology of this abnormality is not well understood but the possibility that it is secondary to the stress of nutrient overload has been suggested. To test this hypoth...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Diabetologia
Hauptverfasser: Toledo, Frederico G. S., Johannsen, Darcy L., Covington, Jeffrey D., Bajpeyi, Sudip, Goodpaster, Bret, Conley, Kevin E., Ravussin, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770194/
https://ncbi.nlm.nih.gov/pubmed/29150696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4496-8
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