Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content Is Related to Insulin Sensitivity After 8-Weeks of Overfeeding

OBJECTIVE: Intramyocellular lipid (IMCL) is inversely related to insulin sensitivity in sedentary populations, yet no prospective studies in humans have examined IMCL accumulation with overfeeding. METHODS: Twenty-nine males were overfed a high-fat diet (140% caloric intake, 44% from fat) for 8-week...

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Gepubliceerd in:Obesity (Silver Spring)
Hoofdauteurs: Covington, Jeffrey D., Johannsen, Darcy L., Coen, Paul M., Burk, David H., Obanda, Diana N., Ebenezer, Philip J., Tam, Charmaine S., Goodpaster, Bret H., Ravussin, Eric, Bajpeyi, Sudip
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705570/
https://ncbi.nlm.nih.gov/pubmed/29071793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21980
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