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Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals

AIMS/HYPOTHESES: Reduced mitochondrial capacity in skeletal muscle has been observed in obesity and type 2 diabetes. In humans, the aetiology of this abnormality is not well understood but the possibility that it is secondary to the stress of nutrient overload has been suggested. To test this hypoth...

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Bibliographic Details
Published in:Diabetologia
Main Authors: Toledo, Frederico G. S., Johannsen, Darcy L., Covington, Jeffrey D., Bajpeyi, Sudip, Goodpaster, Bret, Conley, Kevin E., Ravussin, Eric
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770194/
https://ncbi.nlm.nih.gov/pubmed/29150696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4496-8
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