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Hydrophobic Effect from Conjugated Chemicals or Drugs on In Vivo Biodistribution of RNA Nanoparticles

Liver or other organ accumulation of drugs is one of the major problems that leads to toxicity and side effects in therapy using chemicals or other macromolecules. It has been shown that specially designed RNA nanoparticles can specifically target cancer cells, silence oncogenic genes, and stop canc...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Jasinski, Daniel L., Yin, Hongran, Li, Zhefeng, Guo, Peixuan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770098/
https://ncbi.nlm.nih.gov/pubmed/28557574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.054
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