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Hydrophobic Effect from Conjugated Chemicals or Drugs on In Vivo Biodistribution of RNA Nanoparticles

Liver or other organ accumulation of drugs is one of the major problems that leads to toxicity and side effects in therapy using chemicals or other macromolecules. It has been shown that specially designed RNA nanoparticles can specifically target cancer cells, silence oncogenic genes, and stop canc...

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Détails bibliographiques
Publié dans:Hum Gene Ther
Auteurs principaux: Jasinski, Daniel L., Yin, Hongran, Li, Zhefeng, Guo, Peixuan
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770098/
https://ncbi.nlm.nih.gov/pubmed/28557574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.054
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