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Hydrophobic Effect from Conjugated Chemicals or Drugs on In Vivo Biodistribution of RNA Nanoparticles

Liver or other organ accumulation of drugs is one of the major problems that leads to toxicity and side effects in therapy using chemicals or other macromolecules. It has been shown that specially designed RNA nanoparticles can specifically target cancer cells, silence oncogenic genes, and stop canc...

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書目詳細資料
發表在:Hum Gene Ther
Main Authors: Jasinski, Daniel L., Yin, Hongran, Li, Zhefeng, Guo, Peixuan
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770098/
https://ncbi.nlm.nih.gov/pubmed/28557574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.054
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