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Evaluation of Intrathecal Routes of Administration for Adeno-Associated Viral Vectors in Large Animals

Delivery of adeno-associated viral (AAV) vectors into the cerebrospinal fluid (CSF) can achieve gene transfer to cells throughout the brain and spinal cord, potentially making many neurological diseases tractable gene therapy targets. Identifying the optimal route of CSF access for intrathecal AAV d...

詳細記述

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書誌詳細
出版年:Hum Gene Ther
主要な著者: Hinderer, Christian, Bell, Peter, Katz, Nathan, Vite, Charles H., Louboutin, Jean-Pierre, Bote, Erin, Yu, Hongwei, Zhu, Yanqing, Casal, Margret L., Bagel, Jessica, O'Donnell, Patricia, Wang, Ping, Haskins, Mark E., Goode, Tamara, Wilson, James M.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770082/
https://ncbi.nlm.nih.gov/pubmed/28806897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.026
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