Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene

[Image: see text] A cellular protease-mediated graphene-based nanosystem is developed for co-delivery of a membrane-associated cytokine (TRAIL) and an intracellular-acting small-molecule drug (DOX). The nanocarrier realizes the intramembrane enzyme-mediated extracellular release of TRAIL and endocyt...

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Bibliografische gegevens
Gepubliceerd in:Adv Mater
Hoofdauteurs: Jiang, Tianyue, Sun, Wujin, Zhu, Qiuwen, Burns, Nancy A., Khan, Saad A., Mo, Ran, Gu, Zhen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769919/
https://ncbi.nlm.nih.gov/pubmed/25504623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201404498
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