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Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene
[Image: see text] A cellular protease-mediated graphene-based nanosystem is developed for co-delivery of a membrane-associated cytokine (TRAIL) and an intracellular-acting small-molecule drug (DOX). The nanocarrier realizes the intramembrane enzyme-mediated extracellular release of TRAIL and endocyt...
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| Publié dans: | Adv Mater |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5769919/ https://ncbi.nlm.nih.gov/pubmed/25504623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201404498 |
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