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Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

[Image: see text] A bioinspired cocoon-like anticancer drug delivery system consisting of a deoxyribonuclease (DNase)-degradable DNA nanoclew (NCl) embedded with an acid-responsive DNase I nanocapsule (NCa) was developed for targeted cancer treatment. The NCl was assembled from a long-chain single-s...

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Detalhes bibliográficos
Main Authors: Sun, Wujin, Jiang, Tianyue, Lu, Yue, Reiff, Margaret, Mo, Ran, Gu, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210150/
https://ncbi.nlm.nih.gov/pubmed/25336272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5088024
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