The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes

The mammalian HoxD cluster lies between two topologically associating domains (TADs) matching distinct enhancer-rich regulatory landscapes. During limb development, the telomeric TAD controls the early transcription of Hoxd genes in forearm cells, whereas the centromeric TAD subsequently regulates m...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Rodríguez-Carballo, Eddie, Lopez-Delisle, Lucille, Zhan, Ye, Fabre, Pierre J., Beccari, Leonardo, El-Idrissi, Imane, Huynh, Thi Hanh Nguyen, Ozadam, Hakan, Dekker, Job, Duboule, Denis
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769770/
https://ncbi.nlm.nih.gov/pubmed/29273679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.307769.117
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