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Rare variant association analysis in case-parents studies by allowing for missing parental genotypes
BACKGROUND: The development of next-generation sequencing technologies has facilitated the identification of rare variants. Family-based design is commonly used to effectively control for population admixture and substructure, which is more prominent for rare variants. Case-parents studies, as typic...
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| Publicado no: | BMC Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5769338/ https://ncbi.nlm.nih.gov/pubmed/29334894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-018-0597-8 |
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