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Congenital anomalies in neurofibromatosis 1: a retrospective register-based total population study

BACKGROUND: Neurofibromatosis type 1 (NF1) is a dominantly inherited Rasopathy caused by mutations in the NF1 gene on chromosome 17. NF1 has been connected to congenital anomalies, e.g., in the skeletal and cardiovascular systems, but the overall incidence of anomalies is unknown. In this retrospect...

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Dades bibliogràfiques
Publicat a:Orphanet J Rare Dis
Autors principals: Leppävirta, Jussi, Kallionpää, Roope A., Uusitalo, Elina, Vahlberg, Tero, Pöyhönen, Minna, Peltonen, Juha, Peltonen, Sirkku
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769274/
https://ncbi.nlm.nih.gov/pubmed/29335026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-017-0756-4
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