Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain

Eitemau Tebyg

• Discovery of a Potent and Efficacious Peptide Derivative for δ/μ Opioid Agonist/Neurokinin 1 Antagonist Activity with a 2′, 6′-Dimethyl-L-Tyrosine: In Vitro, In Vivo and NMR-Based Structural Studies
  gan: Yamamoto, Takashi, et al.
  Cyhoeddwyd: (2011)
• A Structure–Activity Relationship Study and Combinatorial Synthetic Approach of C-Terminal Modified Bifunctional Peptides That Are δ/μ Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists
  gan: Yamamoto, Takashi, et al.
  Cyhoeddwyd: (2008)
• Investigational peptide and peptidomimetic μ and δ opioid receptor agonists in the relief of pain
  gan: Giri, Aswini Kumar, et al.
  Cyhoeddwyd: (2013)
• The Importance of Micelle-Bound States for the Bioactivities of Bifunctional Peptide Derivatives for δ/μ Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists
  gan: Yamamoto, Takashi, et al.
  Cyhoeddwyd: (2008)
• Design, Synthesis, and Biological Evaluation of Novel Bifunctional C-Terminal-Modified Peptides for δ/μ Opioid Receptor Agonists and Neurokinin-1 Receptor Antagonists
  gan: Yamamoto, Takashi, et al.
  Cyhoeddwyd: (2007)