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Oral bioavailability of DN101, a concentrated formulation of calcitriol, in tumor-bearing dogs

PURPOSE: High-dose calcitriol (1,25-dihydroxyvitamin D(3)) has antineoplastic activity against a range of tumors and potentiates chemotherapeutic agents. In an earlier canine study, the MTD of intravenous (i.v.) calcitriol was 3.75 μg/kg, but polysorbate-associated hypersensitivity reactions were co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Chemother Pharmacol
Prif Awduron: Rassnick, Kenneth M., Muindi, Josephia R., Johnson, Candace S., Bailey, Dennis B., Trump, Donald L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769150/
https://ncbi.nlm.nih.gov/pubmed/20306264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1304-2
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