In vitro and in vivo evaluation of combined calcitriol and cisplatin in dogs with spontaneously occurring tumors

PURPOSE: Calcitriol potentiates cisplatin-mediated activity in a variety of tumor models. We examine here, the effect of calcitriol and cisplatin pre-clinically and clinically in canine spontaneous tumors through in vitro studies on tumor cells and through a phase I study of calcitriol and cisplatin...

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Hauptverfasser: Rassnick, Kenneth M., Muindi, Josephia R., Johnson, Candace S., Balkman, Cheryl E., Ramnath, Nithya, Yu, Wei-Dong, Engler, Kristie L., Page, Rodney L., Trump, Donald L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715945/
https://ncbi.nlm.nih.gov/pubmed/18246349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0678-x
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