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Oral bioavailability of DN101, a concentrated formulation of calcitriol, in tumor-bearing dogs
PURPOSE: High-dose calcitriol (1,25-dihydroxyvitamin D(3)) has antineoplastic activity against a range of tumors and potentiates chemotherapeutic agents. In an earlier canine study, the MTD of intravenous (i.v.) calcitriol was 3.75 μg/kg, but polysorbate-associated hypersensitivity reactions were co...
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| Publicado no: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5769150/ https://ncbi.nlm.nih.gov/pubmed/20306264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1304-2 |
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