Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes

Inwardly rectifying potassium (Kir) 4.1 channels in astrocytes regulate neuronal excitability by mediating spatial potassium buffering. Although dysfunction of astrocytic Kir4.1 channels is implicated in the development of epileptic seizures, the functional mechanisms of Kir4.1 channels in modulatin...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Kinboshi, Masato, Mukai, Takahiro, Nagao, Yuki, Matsuba, Yusuke, Tsuji, Yoshimi, Tanaka, Shiho, Tokudome, Kentaro, Shimizu, Saki, Ito, Hidefumi, Ikeda, Akio, Inanobe, Atsushi, Kurachi, Yoshihisa, Inoue, Seiji, Ohno, Yukihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768989/
https://ncbi.nlm.nih.gov/pubmed/29358904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00408
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