Effect of a calcitonin gene-related peptide-binding L-RNA aptamer on neuronal activity in the rat spinal trigeminal nucleus

BACKGROUND: Calcitonin gene-related peptide (CGRP) plays a major role in the pathogenesis of migraine and other primary headaches. Spinal trigeminal neurons integrate nociceptive afferent input from trigeminal tissues including intracranial afferents, and their activity is thought to reflect facial...

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Detalhes bibliográficos
Publicado no:J Headache Pain
Main Authors: Fischer, Michael J. M., Schmidt, Jakob, Koulchitsky, Stanislav, Klussmann, Sven, Vater, Axel, Messlinger, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Milan 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768576/
https://ncbi.nlm.nih.gov/pubmed/29335794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-018-0832-8
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