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Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice

Trimetazidine (TMZ) is a metabolic reprogramming agent able to partially inhibit mitochondrial free fatty acid β-oxidation while enhancing glucose oxidation. Here we have found that the metabolic shift driven by TMZ enhances the myogenic potential of skeletal muscle progenitor cells leading to MyoD,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncotarget
मुख्य लेखकों: Gatta, Lucia, Vitiello, Laura, Gorini, Stefania, Chiandotto, Sergio, Costelli, Paola, Giammarioli, Anna Maria, Malorni, Walter, Rosano, Giuseppe, Ferraro, Elisabetta
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768376/
https://ncbi.nlm.nih.gov/pubmed/29371959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23044
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