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The EPAC–Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability
Increased retinal vascular permeability contributes to macular edema, a leading cause of vision loss in eye pathologies such as diabetic retinopathy, age-related macular degeneration, and central retinal vein occlusions. Pathological changes in vascular permeability are driven by growth factors such...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767874/ https://ncbi.nlm.nih.gov/pubmed/29158262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815381 |
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