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Mitochondrial intermediate peptidase is a novel regulator of sirtuin‐3 activation by caloric restriction
Sirtuin‐3 (SIRT3) regulates mitochondrial quality and is involved in the anti‐ageing and pro‐longevity actions of caloric restriction (CR). Here, we show that CR upregulates the mature form of SIRT3 and mitochondrial intermediate peptidase (MIPEP), a mitochondrial signal peptidase (MtSPase), in whit...
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767765/ https://ncbi.nlm.nih.gov/pubmed/29151261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12914 |
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