Mitochondrial intermediate peptidase is a novel regulator of sirtuin‐3 activation by caloric restriction

Sirtuin‐3 (SIRT3) regulates mitochondrial quality and is involved in the anti‐ageing and pro‐longevity actions of caloric restriction (CR). Here, we show that CR upregulates the mature form of SIRT3 and mitochondrial intermediate peptidase (MIPEP), a mitochondrial signal peptidase (MtSPase), in whit...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Kobayashi, Masaki, Takeda, Kanae, Narita, Takumi, Nagai, Keita, Okita, Naoyuki, Sudo, Yuka, Miura, Yuri, Tsumoto, Hiroki, Nakagawa, Yoshimi, Shimano, Hitoshi, Higami, Yoshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Letters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767765/
https://ncbi.nlm.nih.gov/pubmed/29151261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12914
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