Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import

BACKGROUND: Combination antiretroviral therapy efficiently suppresses HIV replication in infected patients, transforming HIV/AIDS into a chronic disease. Viral resistance does develop however, especially under suboptimal treatment conditions such as poor adherence. As a consequence, continued explor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Retrovirology
Prif Awduron: Demeulemeester, Jonas, Blokken, Jolien, De Houwer, Stéphanie, Dirix, Lieve, Klaassen, Hugo, Marchand, Arnaud, Chaltin, Patrick, Christ, Frauke, Debyser, Zeger
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767004/
https://ncbi.nlm.nih.gov/pubmed/29329553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-018-0389-2
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