Inhibitors of the integrase–transportin-SR2 interaction block HIV nuclear import

BACKGROUND: Combination antiretroviral therapy efficiently suppresses HIV replication in infected patients, transforming HIV/AIDS into a chronic disease. Viral resistance does develop however, especially under suboptimal treatment conditions such as poor adherence. As a consequence, continued explor...

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Publicado en:Retrovirology
Autores principales: Demeulemeester, Jonas, Blokken, Jolien, De Houwer, Stéphanie, Dirix, Lieve, Klaassen, Hugo, Marchand, Arnaud, Chaltin, Patrick, Christ, Frauke, Debyser, Zeger
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767004/
https://ncbi.nlm.nih.gov/pubmed/29329553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-018-0389-2
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