Probing the metastable state of influenza hemagglutinin

Viral entry into host cells is mediated by membrane proteins in a metastable state that transition to a more stable state upon a stimulus. For example, in the influenza envelope protein hemagglutinin (HA), the low pH in the endosome triggers a transition from the metastable prefusion conformation to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Kingsley, Carolyn N., Antanasijevic, Aleksandar, Palka-Hamblin, Helena, Durst, Matthew, Ramirez, Benjamin, Lavie, Arnon, Caffrey, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766969/
https://ncbi.nlm.nih.gov/pubmed/29127198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815043
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