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Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins

The molecular seal between epithelial cells, called the tight junction (TJ), is built by several membrane proteins, with claudins playing the most prominent role. The scaffold proteins of the zonula occludens family are required for the correct localization of claudins and hence formation of the TJ....

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Nomme, Julian, Antanasijevic, Aleksandar, Caffrey, Michael, Van Itallie, Christina M., Anderson, James M., Fanning, Alan S., Lavie, Arnon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505413/
https://ncbi.nlm.nih.gov/pubmed/26023235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646695
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