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Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins

The molecular seal between epithelial cells, called the tight junction (TJ), is built by several membrane proteins, with claudins playing the most prominent role. The scaffold proteins of the zonula occludens family are required for the correct localization of claudins and hence formation of the TJ....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nomme, Julian, Antanasijevic, Aleksandar, Caffrey, Michael, Van Itallie, Christina M., Anderson, James M., Fanning, Alan S., Lavie, Arnon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505413/
https://ncbi.nlm.nih.gov/pubmed/26023235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646695
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