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Loss of the mucosal barrier alters the progenitor cell niche via Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling

The mucous barrier of our digestive tract is the first line of defense against pathogens and damage. Disruptions in this barrier are associated with diseases such as Crohn's disease, colitis, and colon cancer, but mechanistic insights into these processes and diseases are limited. We have previ...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Liping, Turner, Bradley, Ribbeck, Katharina, Ten Hagen, Kelly G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766965/
https://ncbi.nlm.nih.gov/pubmed/29127201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809848
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