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Loss of the mucosal barrier alters the progenitor cell niche via Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling

The mucous barrier of our digestive tract is the first line of defense against pathogens and damage. Disruptions in this barrier are associated with diseases such as Crohn's disease, colitis, and colon cancer, but mechanistic insights into these processes and diseases are limited. We have previ...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Zhang, Liping, Turner, Bradley, Ribbeck, Katharina, Ten Hagen, Kelly G.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766965/
https://ncbi.nlm.nih.gov/pubmed/29127201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809848
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