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hERG1a and hERG1b potassium channel subunits directly interact and preferentially form heteromeric channels

Voltage-activated human ether-á-go-go–related gene (hERG) potassium channels are critical for the repolarization of cardiac action potentials and tune-spike frequency adaptation in neurons. Two isoforms of mammalian ERG1 channel subunits, ERG1a and ERG1b, are the principal subunits that conduct the...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: McNally, Beth A., Pendon, Zeus D., Trudeau, Matthew C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766944/
https://ncbi.nlm.nih.gov/pubmed/29089383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.816488
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