MicroRNA-874–mediated inhibition of the major G(1)/S phase cyclin, CCNE1, is lost in osteosarcomas

The tumor microenvironment is characterized by nutrient-deprived conditions in which the cancer cells have to adapt for survival. Serum starvation resembles the growth factor deprivation characteristic of the poorly vascularized tumor microenvironment and has aided in the discovery of key growth reg...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Ghosh, Tanushree, Varshney, Akhil, Kumar, Praveen, Kaur, Manpreet, Kumar, Vipin, Shekhar, Ritu, Devi, Raksha, Priyanka, Priyanka, Khan, Md. Muntaz, Saxena, Sandeep
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766939/
https://ncbi.nlm.nih.gov/pubmed/29109143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808287
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