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MicroRNA-874–mediated inhibition of the major G(1)/S phase cyclin, CCNE1, is lost in osteosarcomas

The tumor microenvironment is characterized by nutrient-deprived conditions in which the cancer cells have to adapt for survival. Serum starvation resembles the growth factor deprivation characteristic of the poorly vascularized tumor microenvironment and has aided in the discovery of key growth reg...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ghosh, Tanushree, Varshney, Akhil, Kumar, Praveen, Kaur, Manpreet, Kumar, Vipin, Shekhar, Ritu, Devi, Raksha, Priyanka, Priyanka, Khan, Md. Muntaz, Saxena, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766939/
https://ncbi.nlm.nih.gov/pubmed/29109143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808287
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