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MicroRNA-874–mediated inhibition of the major G(1)/S phase cyclin, CCNE1, is lost in osteosarcomas
The tumor microenvironment is characterized by nutrient-deprived conditions in which the cancer cells have to adapt for survival. Serum starvation resembles the growth factor deprivation characteristic of the poorly vascularized tumor microenvironment and has aided in the discovery of key growth reg...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766939/ https://ncbi.nlm.nih.gov/pubmed/29109143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808287 |
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