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The microRNAs miR-449a and miR-424 suppress osteosarcoma by targeting cyclin A2 expression

MicroRNAs of the miR-16 and miR-34 families have been reported to inhibit cell cycle progression, and their loss has been linked to oncogenic transformation. Utilizing a high-throughput, genome-wide screen for miRNAs and mRNAs that are differentially regulated in osteosarcoma (OS) cell lines, we rep...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Shekhar, Ritu, Priyanka, Priyanka, Kumar, Praveen, Ghosh, Tanushree, Khan, Md. Muntaz, Nagarajan, Perumal, Saxena, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433048/
https://ncbi.nlm.nih.gov/pubmed/30679313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005778
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