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Jumpstarting the cytochrome P450 catalytic cycle with a hydrated electron

Cytochrome P450cam (CYP101Fe(3+)) regioselectively hydroxylates camphor. Possible hydroxylating intermediates in the catalytic cycle of this well-characterized enzyme have been proposed on the basis of experiments carried out at very low temperatures and shunt reactions, but their presence has not y...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Erdogan, Huriye, Vandemeulebroucke, An, Nauser, Thomas, Bounds, Patricia L., Koppenol, Willem H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766938/
https://ncbi.nlm.nih.gov/pubmed/29109145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813683
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