Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

Extracellular vesicles (EVs) carry RNA, DNA, proteins, and lipids. Specifically, tumor-derived EVs have the potential to be utilized as disease-specific biomarkers. However, a lack of methods to isolate tumor-specific EVs has limited their use in clinical settings. Here we report a sensitive analyti...

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Publié dans:Nat Commun
Auteurs principaux: Reátegui, Eduardo, van der Vos, Kristan E., Lai, Charles P., Zeinali, Mahnaz, Atai, Nadia A., Aldikacti, Berent, Floyd, Frederick P., H. Khankhel, Aimal, Thapar, Vishal, Hochberg, Fred H., Sequist, Lecia V., Nahed, Brian V., S. Carter, Bob, Toner, Mehmet, Balaj, Leonora, T. Ting, David, Breakefield, Xandra O., Stott, Shannon L.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766611/
https://ncbi.nlm.nih.gov/pubmed/29330365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02261-1
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