Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

Extracellular vesicles (EVs) carry RNA, DNA, proteins, and lipids. Specifically, tumor-derived EVs have the potential to be utilized as disease-specific biomarkers. However, a lack of methods to isolate tumor-specific EVs has limited their use in clinical settings. Here we report a sensitive analyti...

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Publicado no:Nat Commun
Main Authors: Reátegui, Eduardo, van der Vos, Kristan E., Lai, Charles P., Zeinali, Mahnaz, Atai, Nadia A., Aldikacti, Berent, Floyd, Frederick P., H. Khankhel, Aimal, Thapar, Vishal, Hochberg, Fred H., Sequist, Lecia V., Nahed, Brian V., S. Carter, Bob, Toner, Mehmet, Balaj, Leonora, T. Ting, David, Breakefield, Xandra O., Stott, Shannon L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766611/
https://ncbi.nlm.nih.gov/pubmed/29330365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02261-1
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