Microfluidic isolation of platelet-covered circulating tumor cells

The interplay between platelets and tumor cells is known to play important roles in metastasis by enhancing tumor cell survival, tumor-vascular interactions, and escape from immune surveillance. However, platelet-covered circulating tumor cells (CTC) are extremely difficult to isolate due to masking...

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Veröffentlicht in:Lab Chip
Hauptverfasser: Jiang, Xiaocheng, Wong, Keith H. K., Khankhel, Aimal H., Zeinali, Mahnaz, Reategui, Eduardo, Phillips, Matthew J., Luo, Xi, Aceto, Nicola, Fachin, Fabio, Hoang, Anh N., Kim, Wooseok, Jensen, Annie E., Sequist, Lecia V., Maheswaran, Shyamala, Haber, Daniel A., Stott, Shannon L., Toner, Mehmet
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690580/
https://ncbi.nlm.nih.gov/pubmed/28932842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7lc00654c
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