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Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice

To improve the safety and efficacy of oral rotavirus vaccines, we developed an inactivated rotavirus vaccine (IRV) for parenteral administration. Since it remains unknown whether parenteral vaccination can induce mucosal immunity, we performed a comprehensive assessment of immune responses to IRV in...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Resch, Theresa K., Wang, Yuhuan, Moon, Sung-Sil, Joyce, Jessica, Li, Song, Prausnitz, Mark, Jiang, Baoming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766576/
https://ncbi.nlm.nih.gov/pubmed/29330512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18973-9
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