Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters.

Clostridium difficile produces toxins that cause inflammation, necrosis, and fluid in the intestine and is the most important cause of nosocomial antibiotic-associated diarrhea and colitis. We evaluated C. difficile antigens as vaccines to protect against systemic and intestinal disease in a hamster...

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Vydáno v:	Infect Immun
Hlavní autoři:	Torres, J F, Lyerly, D M, Hill, J E, Monath, T P
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1995
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.12.4619-4627.1995
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