Clostridium difficile Vaccine and Serum Immunoglobulin G Antibody Response to Toxin A

There is a strong association between serum antibody responses to toxin A and protection against Clostridium difficile diarrhea. A parenteral C. difficile toxoid vaccine induced very-high-level responses to anti-toxin A immunoglobulin G (IgG) in the sera of healthy volunteers. After vaccination, the...

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Main Authors: Aboudola, Samer, Kotloff, Karen L., Kyne, Lorraine, Warny, Michel, Kelly, Eoin C., Sougioultzis, Stavros, Giannasca, Paul J., Monath, Thomas P., Kelly, Ciarán P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC148861/
https://ncbi.nlm.nih.gov/pubmed/12595488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1608-1610.2003
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