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Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters.

Clostridium difficile produces toxins that cause inflammation, necrosis, and fluid in the intestine and is the most important cause of nosocomial antibiotic-associated diarrhea and colitis. We evaluated C. difficile antigens as vaccines to protect against systemic and intestinal disease in a hamster...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Torres, J F, Lyerly, D M, Hill, J E, Monath, T P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173664/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.12.4619-4627.1995
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