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Dose sparing and enhanced immunogenicity of inactivated rotavirus vaccine administered by skin vaccination using a microneedle patch()

Skin immunization is effective against a number of infectious diseases, including smallpox and tuberculosis, but is difficult to administer. Here, we assessed the use of an easy-to-administer microneedle (MN) patch for skin vaccination using an inactivated rotavirus vaccine (IRV) in mice. Female inb...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Moon, Sungsil, Wang, Yuhuan, Edens, Chris, Gentsch, Jon R., Prausnitz, Mark R., Jiang, Baoming
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610374/
https://ncbi.nlm.nih.gov/pubmed/23174199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.11.027
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