HLA-B, HLA-C and KIR improve the predictive value of IFNL3 for Hepatitis C spontaneous clearance

IFNL3 is the strongest predictor of spontaneous resolution (SR) of hepatitis C virus (HCV), however, consideration of IFNL3 genotype alone is of limited clinical value for the prediction of SR or chronic HCV infection. The objective of this study was to analyze the impact of HLA-B, HLA-C and KIRs on...

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Udgivet i:Sci Rep
Main Authors: Frias, Mario, Rivero-Juárez, Antonio, Rodriguez-Cano, Diego, Camacho, Ángela, López-López, Pedro, Risalde, María Ángeles, Manzanares-Martín, Bárbara, Brieva, Teresa, Machuca, Isabel, Rivero, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766528/
https://ncbi.nlm.nih.gov/pubmed/29330418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17531-7
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