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Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR

The mechanistic Target of Rapamycin (mTOR) signalling network is an evolutionarily conserved network that controls key cellular processes, including cell growth and metabolism. Consisting of the major kinase complexes mTOR Complex 1 and 2 (mTORC1/2), the mTOR network harbours complex interactions an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Varusai, Thawfeek M., Nguyen, Lan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766521/
https://ncbi.nlm.nih.gov/pubmed/29330362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18400-z
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