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Deptor: not only a mTOR inhibitor

Deptor is an important protein that belongs to the mTORC1 and mTORC2 complexes, able to interact with mTOR and to inhibit its kinase activity. As a natural mTOR inhibitor, Deptor is involved in several molecular pathways, such as cell growth, apoptosis, autophagy and ER stress response. For this rea...

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Библиографические подробности
Опубликовано в: :J Exp Clin Cancer Res
Главные авторы: Catena, Valeria, Fanciulli, Maurizio
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237168/
https://ncbi.nlm.nih.gov/pubmed/28086984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0484-y
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