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Deptor: not only a mTOR inhibitor
Deptor is an important protein that belongs to the mTORC1 and mTORC2 complexes, able to interact with mTOR and to inhibit its kinase activity. As a natural mTOR inhibitor, Deptor is involved in several molecular pathways, such as cell growth, apoptosis, autophagy and ER stress response. For this rea...
Gespeichert in:
| Veröffentlicht in: | J Exp Clin Cancer Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5237168/ https://ncbi.nlm.nih.gov/pubmed/28086984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0484-y |
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