Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

Copper(II) ternary complex, [Cu(phen)(C-dmg)(H(2)O)]NO(3) was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma xenograft models as well as for toxicity in NOD scid gamma mice. The Cu(II) complex displayed broad spectrum cytotoxicity against multiple ca...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ahmad, Munirah, Suhaimi, Shazlan-Noor, Chu, Tai-Lin, Abdul Aziz, Norazlin, Mohd Kornain, Noor-Kaslina, Samiulla, D. S., Lo, Kwok-Wai, Ng, Chew-Hee, Khoo, Alan Soo-Beng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766233/
https://ncbi.nlm.nih.gov/pubmed/29329342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191295
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