Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

Copper(II) ternary complex, [Cu(phen)(C-dmg)(H(2)O)]NO(3) was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma xenograft models as well as for toxicity in NOD scid gamma mice. The Cu(II) complex displayed broad spectrum cytotoxicity against multiple ca...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ahmad, Munirah, Suhaimi, Shazlan-Noor, Chu, Tai-Lin, Abdul Aziz, Norazlin, Mohd Kornain, Noor-Kaslina, Samiulla, D. S., Lo, Kwok-Wai, Ng, Chew-Hee, Khoo, Alan Soo-Beng
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766233/
https://ncbi.nlm.nih.gov/pubmed/29329342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191295
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