Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma

In this study, we first performed whole exome sequencing of DNA from 10 untreated and clinically annotated fresh frozen nasopharyngeal carcinoma (NPC) biopsies and matched bloods to identify somatically mutated genes that may be amenable to targeted therapeutic strategies. We identified a total of 3...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chow, Yock Ping, Tan, Lu Ping, Chai, San Jiun, Abdul Aziz, Norazlin, Choo, Siew Woh, Lim, Paul Vey Hong, Pathmanathan, Rajadurai, Mohd Kornain, Noor Kaslina, Lum, Chee Lun, Pua, Kin Choo, Yap, Yoke Yeow, Tan, Tee Yong, Teo, Soo Hwang, Khoo, Alan Soo-Beng, Patel, Vyomesh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335658/
https://ncbi.nlm.nih.gov/pubmed/28256603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42980
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