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A Genome Wide Study of Copy Number Variation Associated with Nasopharyngeal Carcinoma in Malaysian Chinese Identifies CNVs at 11q14.3 and 6p21.3 as Candidate Loci

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a neoplasm of the epithelial lining of the nasopharynx. Despite various reports linking genomic variants to NPC predisposition, very few reports were done on copy number variations (CNV). CNV is an inherent structural variation that has been found to be...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Low, Joyce Siew Yong, Chin, Yoon Ming, Mushiroda, Taisei, Kubo, Michiaki, Govindasamy, Gopala Krishnan, Pua, Kin Choo, Yap, Yoke Yeow, Yap, Lee Fah, Subramaniam, Selva Kumar, Ong, Cheng Ai, Tan, Tee Yong, Khoo, Alan Soo Beng, Ng, Ching Ching
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701378/
https://ncbi.nlm.nih.gov/pubmed/26730743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145774
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