The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8(+) T Cells via SHIP-1

We report here that the expression of the transcription factor T-bet, which is known to be required for effector cytotoxic CD8(+) T lymphocytes (CTL) generation and effector memory cell formation, is regulated in CTL by microRNA-155 (miR-155). Importantly, we show that the proliferative effect of mi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hope, Jennifer L., Stairiker, Christopher J., Spantidea, Panagiota I., Gracias, Donald T., Carey, Alison J., Fike, Adam J., van Meurs, Marjan, Brouwers-Haspels, Inge, Rijsbergen, Laurine C., Fraietta, Joseph A., Mueller, Yvonne M., Klop, Rosemarieke C., Stelekati, Erietta, Wherry, E. John, Erkeland, Stefan J., Katsikis, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765282/
https://ncbi.nlm.nih.gov/pubmed/29358931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01696
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