Functional Antibody Response Against V1V2 and V3 of HIV gp120 in the VAX003 and VAX004 Vaccine Trials

Immunization with HIV AIDSVAX gp120 vaccines in the phase III VAX003 and VAX004 trials did not confer protection. To understand the shortcomings in antibody (Ab) responses induced by these vaccines, we evaluated the kinetics of Ab responses to the V1V2 and V3 regions of gp120 and the induction of Ab...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Balasubramanian, Preetha, Williams, Constance, Shapiro, Mariya B., Sinangil, Faruk, Higgins, Keith, Nádas, Arthur, Totrov, Maxim, Kong, Xiang-Peng, Fiore-Gartland, Andrew J., Haigwood, Nancy L., Zolla-Pazner, Susan, Hioe, Catarina E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765017/
https://ncbi.nlm.nih.gov/pubmed/29323175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18863-0
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