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Estimated Secondary Structure Propensities within V1/V2 Region of HIV gp120 Are an Important Global Antibody Neutralization Sensitivity Determinant
BACKGROUND: Neutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly between the isolates. Significant role of V1/V2 domain as a global neutralization sensitivity regulator has been suggested. Recent X-ray structures revealed presence of well-defined tertiary structure wi...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976368/ https://ncbi.nlm.nih.gov/pubmed/24705879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094002 |
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