Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor

Angiopoietin-1 (Ang1) and Angiopoietin-2 (Ang2) are ligands for Tie2, an endothelial-specific receptor tyrosine kinase that is an essential regulator of angiogenesis. Here we report the identification, via expression cloning, of thrombomodulin (TM) as another receptor for Ang1 and Ang2. Thrombomodul...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Daly, Christopher, Qian, Xiaozhong, Castanaro, Carla, Pasnikowski, Elizabeth, Jiang, Xiabo, Thomson, Benjamin R., Quaggin, Susan E., Papadopoulos, Nicholas, Wei, Yang, Rudge, John S., Thurston, Gavin, Yancopoulos, George D., Davis, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765006/
https://ncbi.nlm.nih.gov/pubmed/29323190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18912-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados