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The STIM-Orai Pathway: Orai, the Pore-Forming Subunit of the CRAC Channel

This chapter focuses on the Orai proteins, Orai1–Orai3, with special emphasis on Orai1, in humans and other mammals, and on the definitive evidence that Orai is the pore subunit of the CRAC channel. It begins by reviewing briefly the defining characteristics of the CRAC channel, then discusses the s...

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Bibliografiske detaljer
Udgivet i:Adv Exp Med Biol
Main Authors: Gudlur, Aparna, Hogan, Patrick G.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764705/
https://ncbi.nlm.nih.gov/pubmed/28900908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-57732-6_3
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